Author Archives: James Carroll

About James Carroll

Founder and CEO at THOR Photomedicine Ltd. About THOR

The Bottom Line – Your phototherapy is not the same as mine

Lilach wrote to me this morning (if you are a regular at LLLT conferences you will know her) and in the dialogue she referred to the “phototherapy community”. I had just downloaded 121 LLLT and other phototherapy papers for this monthly literature watch blog. I had to wade through 99 papers that were not LLLT in order to arrive at 22 that were. Many of those were phototherapy and I thought I should bring them to your attention:

Phototherapy for Neonatal hyperbilirubinemia
Phototherapy for Psoriasis and vitiligo (and many other skin problems)
Phototherapy for Seasonal Effective Disorder or depression
Phototherapy for Vitamin D deficiency
Phototherapy for jet lag and sleep disorders

and to a greater or lesser degree these are already somewhat accepted in mainstream medicine.

Why is it that, and why is LLLT not yet accepted ?

send me a short comment back below.

One word answers are acceptable.

Posted in Rants | 3 Comments

Low Level Laser Therapy LLLT / Cold Laser Literature watch for Dec 2011

22 new papers for your review: RCT on OA knee; systematic review of treatment modalities for neurosensory deficit after lower third molar surgery found LLLT to provide significant improvement; review of transcranial LLLT for neurodegenerative diseases, laser biomodulation of normal and neoplastic cells (another comprehensive study by Farouk Al-Watban with very interesting results); Laser vs LED study on skin flap viability, angiogenesis and mast cells (spoiler alert, LED wins); treatment of dermatitis in 10 koi carp with 980nm laser!; and yet another case of LLLT for burning mouth syndrome.

As it happens, a customer wrote just a minute ago to say that his patient had rapid resolution of burning mouth that lasted 18 hours after the first LED treatment.

Efficacy of low level laser therapy associated with exercises in knee osteoarthritis: a randomized double-blind study.

Alfredo PP, Bjordal JM, Dreyer SH, Meneses SR, Zaguetti G, Ovanessian V, Fukuda TY, Junior WS, Martins RA, Casarotto RA, Marques AP

Department of Speech Therapy, Physical Therapy and Occupational Therapy, School of Medicine, Sao Paulo … Continue reading

Posted in Research | on Low Level Laser Therapy LLLT / Cold Laser Literature watch for Dec 2011

Low Level Laser Therapy LLLT / Cold Laser Literature watch for Nov 2011

21 new LLLT papers for your review this month including:

– How to report LLLT beam & dose parameters
– Bisphosphonate osteonecrosis of the jaw (BRONJ)
– Rotator cuff tendinitis
– The effect of LED on a patient in a persistent vegetative state
– Two papers on herpes simplex
– A study on acneiform rash due to EGFRI
– LLLT for “coronally advanced flap adjunct” (a gingival surgical
procedure)
– Lymphedema Praecox

How to Report Low-Level Laser Therapy (LLLT)/Photomedicine Dose and Beam Parameters in Clinical and Laboratory Studies.

Jenkins PA, Carroll JD

1 SpectraMedics Pty Ltd , Oakbank, SA, Australia ; SpectraVET Inc., Irradia LLC, and Irradia Education Inc., Lawndale, North Carolina; and Immunophotonics Inc., Columbia, Missouri. 2 THOR Photomedicine Ltd, Chesham, United Kingdom

Background: Dose and beam parameters are critical for successful laser, LED, and other light therapy treatments, however, in our experience, researchers frequently make critical errors and omissions when submitting papers for publication. Journals frequently publish studies with … Continue reading

Posted in Research | on Low Level Laser Therapy LLLT / Cold Laser Literature watch for Nov 2011

Low Level Laser Therapy LLLT / Cold Laser Literature watch for Oct 2011

28 new LLLT papers for your review this month, including three from the Hamblin stable at Harvard. First on this list (and one I co-authored) is an invited paper called the “The Nuts and Bolts of Low-level Laser (Light) Therapy“. It’s everything you need to know about the latest thinking on the mechanism of action, beam parameters, dose and where the research is going. Next from the Hamblin lab is a dose response study on cortical neurones and, guess what, once again: less is more. 810nm light (25 mW/cm2) on mouse primary cortical neurons induced a significant increase in calcium, ATP and MMP at lower fluences but decreased them at higher fluences. A beautiful biphasic dose response curve shows that increasing the dose beyond  a certain point (3J/cm2 in this case) showed a decline from the peak effect at 10 and 30J/cm2. The third paper in today’s Hamblin trio compares pulsed and continuous wave 810-nm laser for traumatic brain injury in mice with significant benefits of 10Hz over 100Hz or CW. Whilst on … Continue reading

Posted in Research | 1 Comment

Prof. Micheal Hamblin Harvard Medical School

Low Level Laser Therapy (LLLT) mechanisms and dose response.

Posted in Interviews, Video of the Week | on Prof. Micheal Hamblin Harvard Medical School

LLLT and TRPV1

TRPV1 is a nonselective cation channel involved in nociception. At a pain conference in London I attended last week a speaker reported that about $ billion has been spent by the pharmaceutical industry on developing a new class of analgesics to block this protein. However there is a sided effect on body temperature (hyperthermia) making it unusable which is a shame as the potential benefits are huge read here on Wikipedia.

TRPV1 is new to me and I wondered if perhaps anyone had looked at the effect of LLLT on it and they have. A group in Korea have shown that Er,Cr:YSGG laser has an analgesic effect via TRPV1 inhibition. Well hooray for the Koreans, if they really have discovered Inhibition of TRPV1 with laser (and without hyperthermia), it could become another medical holy grail assailed by LLLT.

Posted in Rants | 5 Comments

Low Level Laser Therapy (LLLT) reduces chemotherapy and radiotherapy induced Oral Mucositis

I have written a short web page on how LLLT reduces chemotherapy and radiotherapy induced Oral Mucositis and provided a white paper you can download so click here to download LLLT reduces chemotherapy and radiotherapy induced Oral Mucositis

Posted in PBM/LLLT | on Low Level Laser Therapy (LLLT) reduces chemotherapy and radiotherapy induced Oral Mucositis