Category Archives: My top five research papers
My Top Five LLLT wound healing papers
First an introduction to Low Level Light Therapy (LLLT) for wound healing.
Low Level Light Therapy (LLLT) improves tissue repair, reduces pain and inflammation wherever the beam is applied. Treatments take a few minutes and should be applied two or more times a week.
LLLT has been used for many years on sports injuries, arthritic joints, back and neck pain, and non-healing wounds such as venous ulcers diabetic foot ulcers and pressure sores as well as post chemotherapy and radiation ulcers (mucositis).
How LLLT works:
Mitochondria in stressed or ischemic tissues synthesise nitric oxide (NOmt) that binds to cytochrome c oxidase competitively displacing oxygen leading to oxidative stress and reduced ATP production.
Light of the correct wavelength when applied to wounds is absorbed by cytochrome c oxidase displacing NOmt thereby reducing oxidative stress and increasing ATP production.
A cascade of downstream metabolic effects have been shown to include increased Ca2+, secretion of growth factors, activation of enzymes & other secondary messengers.
Subsequent increases in cellular activity and mitosis has been shown in vitro … Continue reading
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