Author Archives: James Carroll

About James Carroll

Founder and CEO at THOR Photomedicine Ltd. About THOR

LLLT on hepatic antioxidant defense in acute & chronic diabetic rats

670 nm photobiomodulation reduces acute hepatic oxidative stress by enhancing the antioxidant defence system in diabetic rats

Posted in PBM/LLLT | on LLLT on hepatic antioxidant defense in acute & chronic diabetic rats

LLLT nerve regeneration summary by Shimon Rochkind

Shimon Rochkind is an eminent Israeli neurosurgeon and he is THE pioneer in LLLT nerve regeneration.

He is a specialist in Neurosurgery & Microsurgery, Director of the Division of Peripheral Nerve Reconstruction, Senior Neurosurgeon in the Department of Neurosurgery, Tel-Aviv University, Senior Scientist, Neural & Vascular Institute (N.V.R. labs) and Senior Editor of Photomedicine and Laser Surgery with a formidable international reputation.

Over the past 30 years he has been evaluating the use of phototherapy for intra-operative and post-operative treatment of peripheral nerve injuries. He is also the most delightful, gentle, hard working and committed man you could ever wish to meet.

A prolific author, this latest paper is a digest of his 30 years research

Posted in PBM/LLLT | on LLLT nerve regeneration summary by Shimon Rochkind

LLLT vs ultrasound for Carpal Tunnel Syndrome

Objective was to compare splinting, ultrasound (US), and low-level laser (LLL) in the management of carpal tunnel syndrome (CTS).  A total of 100 hands of 50 women patients with bilateral CTS at 3 months after treatment. LLLT  plus splinting was more advantageous than US therapy plus splinting, especially for the outcomes of lessening of symptom severity, pain alleviation, and increased patient satisfaction.

Posted in PBM/LLLT | on LLLT vs ultrasound for Carpal Tunnel Syndrome

LLLT reduces postoperative trismus and swelling after third molar surgery

RCT evaluation of LLLT on postoperative trismus and edema after third molar extraction on 32 patients.

2mins @ 33 mW/cm2 808nm CW

Conclusion LLLT reduces postoperative trismus and swelling

Posted in PBM/LLLT | on LLLT reduces postoperative trismus and swelling after third molar surgery

Latest LLLT / Cold Laser Literature watch with abstracts Jan 09

Our latest LLLT literature review with 20 abstracts including another muscle fatigue paper from Brazil, two Oral Mucositis papers, a “strong” rating for laser on myofascial trigger points in a Chiropractic systematic review and a Carpal Tunnel Syndrome clinical trial paper.

Posted in PBM/LLLT | on Latest LLLT / Cold Laser Literature watch with abstracts Jan 09

LOW LEVEL LASER / PHOTOBIOMODULATION DOSIMETRY. WHAT ARE THE THRESHOLDS AND WHAT ARE THE LIMITS?

James D Carroll FRSM, AMInstP, THOR Photomedicine Ltd, United Kingdom

Photobiomodulation includes biostimulation and bioinhibition. In vitro, in vivo and clinical studies have established that there are radiant intensities and energy thresholds below which no significant cellular stimulation or clinical effects are achieved.  Conversely there are radiant intensities and total fluence thresholds above which cellular stimulation decreases from its peak effect and inhibition is achieved. Many dose-ranging studies have been published using a variety of laboratory and clinical models and most suggest that cellular stimulation is achieved at radiant intensities in the range of 5 – 50mW/cm2 (at the target tissue ) and that exceeding these levels can inhibit cellular function.

So what is the role of the higher intensity laser products that appear to be popular with some clinicians and their patients ?

Posted in PBM/LLLT, Special Feature | on LOW LEVEL LASER / PHOTOBIOMODULATION DOSIMETRY. WHAT ARE THE THRESHOLDS AND WHAT ARE THE LIMITS?

LED Phototherapy kills MRSA @ 405nm

Congratulations to Chukuka et al for taking the inititive to do this work. The outcomes of this high “dose” / short wavelenght invitro study come as no surprise as this effect has been forecast for some time. For decades that UV light has bactericidal effects but that it can also have carcinogenic effects. 405nm is blue light (just outside the range) so should should be a safer option.

Posted in PBM/LLLT | on LED Phototherapy kills MRSA @ 405nm