LLLT in the Lancet Top 20 Hit Parade

The paper by Roberta Chow, Mark Johnson, Rodrigo Lopes-Martins, Jan M Bjordal titled “Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials” (abstract here) reached number 17 in The Lancet top 20 most downloaded papers for 2010. The full top 20 list is here:

1. Survival as a function of HbA1c in people with type 2 diabetes: a retrospective cohort study
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2. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study
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3. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
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4. Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial
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5. Biological, clinical, and ethical advances of placebo effects
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6. Clinical assessment incorporating a personal genome
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7. Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised controlled trial
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8. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
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9. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial
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10. Ticagrelor in ACS: redefining a new standard of care?
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11. Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial
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12. Use of procalcitonin to reduce patients’ exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial
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13. Apixaban versus enoxaparin for thromboprophylaxis after knee replacement (ADVANCE-2): a randomised double-blind trial
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14. Limitations of the usual blood-pressure hypothesis and importance of variability, instability, and episodic hypertension
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15. Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial
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16. Ageing populations: the challenges ahead
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17. Efficacy of low-level laser therapy in the management of neck pain: a systematic review and meta-analysis of randomised placebo or active-treatment controlled trials
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18. Efficacy and safety of zotarolimus-eluting and sirolimus-eluting coronary stents in routine clinical care (SORT OUT III): a randomised controlled superiority trial
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19. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies
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20. Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials
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