LOW LEVEL LASER / PHOTOBIOMODULATION DOSIMETRY. WHAT ARE THE THRESHOLDS AND WHAT ARE THE LIMITS?

Posted on 9 December 2008 by James Carroll

James D Carroll FRSM, AMInstP, THOR Photomedicine Ltd, United Kingdom

Photobiomodulation includes biostimulation and bioinhibition. In vitro, in vivo and clinical studies have established that there are radiant intensities and energy thresholds below which no significant cellular stimulation or clinical effects are achieved.  Conversely there are radiant intensities and total fluence thresholds above which cellular stimulation decreases from its peak effect and inhibition is achieved. Many dose-ranging studies have been published using a variety of laboratory and clinical models and most suggest that cellular stimulation is achieved at radiant intensities in the range of 5 – 50mW/cm2 (at the target tissue ) and that exceeding these levels can inhibit cellular function.

So what is the role of the higher intensity laser products that appear to be popular with some clinicians and their patients ? Continue reading →

Posted in PBM/LLLT, Special Feature | on LOW LEVEL LASER / PHOTOBIOMODULATION DOSIMETRY. WHAT ARE THE THRESHOLDS AND WHAT ARE THE LIMITS?

LED Phototherapy kills MRSA @ 405nm

Posted on 8 December 2008 by James Carroll

Congratulations to Chukuka et al for taking the inititive to do this work. The outcomes of this high “dose” / short wavelenght invitro study come as no surprise as this effect has been forecast for some time. For decades that UV light has bactericidal effects but that it can also have carcinogenic effects. 405nm is blue light (just outside the range) so should should be a safer option. Continue reading →

Posted in PBM/LLLT | on LED Phototherapy kills MRSA @ 405nm

Latest LLLT literature review with abstracts

Posted on 30 November 2008 by James Carroll

Our latest LLLT literature review with abstracts including muscle fatigue, TMJ, myofacial pain, acne and a possible application for morphine withdrawal.

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Posted in PBM/LLLT | on Latest LLLT literature review with abstracts

Good laser safety advice on Wikipedia

Posted on 15 November 2008 by James Carroll

I stumbled upon the wikipedia entry for laser safety and I consider it to be a good summary. It deals with all classes of lasers, not just Class 3B commonly used in LLLT. http://en.wikipedia.org/wiki/Laser_safety

Posted in PBM/LLLT | on Good laser safety advice on Wikipedia

How much laser is enough? and how much is too much ?

Posted on 29 October 2008 by James Carroll

In a recent systematic review and meta analysis of laser therapy on tendinopathies (Tumilty et al), 11 out of 20 studies failed to produce a positive result. The reason identified for the ineffective studies were that the laser beams were too strong (the irradiance was too high for this particular pathology). Most clinicians are rightly confused about which laser to choose and which dose or technique will work. Continue reading →

Posted in PBM/LLLT, Rants | 2 Comments

Attenuation of morphine withdrawal signs by low level laser therapy in rats

Posted on 20 October 2008 by James Carroll

Scientists at AJA University of Medical Sciences, Tehran have shown that LLLT prior to naloxone injection attenuates the expression of withdrawal signs in morphine-dependent rats.

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Posted in PBM/LLLT | on Attenuation of morphine withdrawal signs by low level laser therapy in rats

Call for papers, NAALT conference June 2009 San Francisco

Posted on 9 October 2008 by James Carroll

It’s time to submit LLLT academic papers and posters for consideration for presentation during the 9th Annual NAALT Conference in 2009:

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Posted in PBM/LLLT | on Call for papers, NAALT conference June 2009 San Francisco