Monthly Archives: July 2008

LLLT using Light Emitting Diodes research list

Posted on 20 July 2008 by James Carroll

Yet another NASA NIR LED therapy paper was published recently showing that LED treatment may be therapeutic to damaged neurons, this time in a Parkinson’s disease model. I thought some of you may not appreciate quite how much research has been conducted with LED’s so here is a list of 43 that I found on PubMed.

Near-infrared light via light-emitting diode treatment is therapeutic against rotenone- and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity.

Liang HL, Whelan HT, Eells JT, Wong-Riley MT

Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

Parkinson’s disease is a common progressive neurodegenerative disorder characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta. Mitochondrial dysfunction has been strongly implicated in the pathogenesis of Parkinson’s disease. Thus, therapeutic approaches that improve mitochondrial function may prove to be beneficial. Previously, we have documented that near-infrared light via light-emitting diode (LED) treatment was therapeutic to neurons functionally inactivated by tetrodotoxin, potassium cyanide (KCN), or methanol intoxication, and LED pretreatment rescued neurons from KCN-induced apoptotic cell … Continue reading →

Posted in Research | on LLLT using Light Emitting Diodes research list

Laser therapy improves vision in patients with Age-related Macular Degeneration

Posted on 15 July 2008 by James Carroll

Low-level laser therapy improves vision in patients with Age-related Macular Degeneration.

Researchers at University of Heidelberg, Germany have conducted a clinical trial on 203 patients with AMD (age-related macular degeneration) and improved visual acuity for between 3 and 36 months.

Posted in PBM/LLLT | 2 Comments

Cold Laser Therapy Mechanisum : On the way to a unified theory

Posted on 12 July 2008 by James Carroll

I just had  chat with Mike Hamblin (Harvard Medical School). He described to me how he had this insight about Nitric Oxide being unbound from Cytochrome C Oxidase by light after reading an article in Nature about fire flies.

Hypoxic or stressed cells tend to be low in oxygen and high in NO
This NO is bound to to Cytochrome C oxidase and inhibits cell function

Light (at certain wavelengths, intensities and duration)  knocks NO off Cytochrome C oxidase so the cell performs optimally again plus the NO causes a temporary increase in blood flow :-)

Posted in PBM/LLLT | on Cold Laser Therapy Mechanisum : On the way to a unified theory

Photobiomodulation / Cold Laser Therapy / LLLT It’s time to name names

Posted on 12 July 2008 by James Carroll

This week Lars Hode and Jan Tunér put out a call for some concensus on the name for this cold laser, low level laser, photobiomodulation thing that we do.They concluded by proposing Laser Phototherapy. I had some counter arguments:

Posted in Rants | on Photobiomodulation / Cold Laser Therapy / LLLT It’s time to name names